Ktji Harrisonburg coalition aims to combat growing meth use by teens, young adults in region

Researchers at VCU Massey Cancer Center have set their sights on a new therapeutic target for an aggressive form of breast cancer with limited trea stanley cup tment options.October is Breast Cancer Awareness Month, and breast cancer is the second most common cancer in U.S. women.Triple-nega stanley thermobecher tive breast cancer is a more aggressive and deadly form of disease that accounts for 10-15 percent of all breast tumors.TNBC grows and spreads more quickly than other breast tumors and is associated with worse patient outcomes, accounting for nearly one-third of all breast cancer-related deaths.Additionally, TNBC affects Black women disproportionately: Black women die from TNBC at a significantly higher rate than white women despite being diagnosed at a younger age.Finding an effective therapy that works well stanley botella in all patients would be an important step in addressing this disparity.Research by Massey scientistsThrough a comprehensive and cutting-edge genomic screening method known as CRISPR/CAS9 screening, Massey scientists 鈥?led by Anthony Faber, Ph.D., and Jennifer Koblinski, Ph.D. 鈥?were able to identify a specific enzyme called UBA1 that revealed itself as an ideal therapeutic target. Using a novel UBA-inhibiting drug called TAK-243, they blocked the cellular function of UBA1 and effectively killed cancer cells in patient-derived breast tumors in mice.Previous research has shown that UBA1 inhibitors can have a positive impact in hematological cancers such as acute myeloid leukemia and chronic myeloge Rkxy Local Events This Weekend

Local fire, law enforcement and emergency medical services per stanley quencher sonnel are teaming with the American Red Cross for the Battle of the Badges blood drive to see who can recruit the vaso stanley most eligible donors in their community to donate blood.Individuals can join the Battle of the Badges blood drive by donating on May 18th from noon 鈥?5:00 p.m. at St. Pauls United Methodist Church. Donors blood donations will help decide who wins bragging rights and a trophy.Battle of the Badges is a friendly competition to encourage community members to join their local first responders and perform their own heroic act with a blood donation. All presenting donors during the blood drive will get to cast a vote to help decide the winner. EMS, fire and law enforcement units know firsthand how important it is to have blood readily available for emergencies, said Bernadette Jay, external communications manager of the Appalachian Blood Services Region. By hosting this blood drive, they are helping ensure that blood is on the shelves before it is needed. The annual Battle of the Badges blood drive began in the area this year. It is supported by various organizations within firefighting, law enforcement and EMS units. Participating in this years competition are: Staunton vaso stanley Police Department, The City of Staunton Fire Department and Staunton-Augusta Rescue Squad.SCHEDULE AN APPOINTMENTTo make an appointment for Staunton Battle of the Badges, use sponsor code: STAUNTON BATTLE, download the Red Cross Blood Donor